menu

Close

MSEP-EX Cell Culture Supplement, Lyophilized

Catalogue no.MSEP-EX

Product Overview

MSEP-EX is an animal-derived component-free (ADCF) cell culture supplement designed to reduce reliance on fetal bovine serum (FBS) and human platelet lysate (hPL). When added to culture medium, MSEP-EX can replace up to 80% of serum without requiring cell adaptation, supporting consistent performance across multiple passages.

Extracted from edible plants, MSEP-EX carries a lower risk of pathogen contamination compared to animal-derived alternatives, making it an ethical and cost-effective choice for biologic production.

Validated cell types include: CHO, RD, MRC5, myoblasts, fibroblasts, epithelial cells, T cells, and mesenchymal stem cells (BM-MSC, UC-MSC).

Applications

  • Biologics Production
  • Virus Production (e.g. enterovirus, lentivirus)
  • Protein Expression Enhancement
  • Cell Culture Medium Supplement
  • Animal Serum Reduction (FBS / hPL)

Key capabilities

  • Reduces FBS or growth factor usage by 50% or more without cell adaptation
  • Promotes cell proliferation across diverse mammalian cell types
  • Enhances protein yield in chemically defined media
  • Increases virus production titers (enterovirus, lentivirus)
  • Supports stem cell culture with maintained doubling time across passages

Instruction to Use

Reconstitute with the basal medium of choice. Recommended working concentration: 4–40 µg/mL. Please refer to the Technical Data Sheet for full reconstitution and usage instructions.

Packing size

20 mg/vial. Other sizes available upon request. Please contact us.

Figures

  • Figure 1. Comparable cell growth profiles between 10% FBS and 2% FBS + MSEP-EX supplement in DMEM are measured after 72 hours incubation
  • Figure 2. Higher yield of protein production in chemical defined medium with MSEP-EX supplement are measured in CHO cell culture.
  • Figure 3. Comparable cell double time in 1% MSEP-EX supplement group in both BM-MSC and UC-MSC cell culture.
  • Figure 4. MSEP-EX supplement increases aging T cell proliferation in primary T cell culture

Features

Source — Plant-based extract
Form — Lyophilized powder
Color — Light yellow to pale white
Solubility (Turbidity) — About 6 mg/mL in sterile water. Slightly cloudy in aqueous solution.
Reconstitution — Reconstitute in the sterile basal medium of choice. Recommended stock concentration: 4 mg/mL
Working Concentration — 4 to 40 µg/mL as supplement in culture medium
Packing Size — 20 mg/vial. Custom packing sizes available upon request — please contact us.
Shipping — Shipped at room temperature.
Stability and Storage — 2 years, below 35°C as lyophilized powder / 2 weeks, 2°C to 8°C under sterile conditions after reconstitution.
 

TDS/COA/MSDS

Cat. No. Product TDS COA MSDS
MSEP-EX Cell culture supplement
MSEP-EX is an animal-derived component-free (ADCF) cell culture supplement designed to reduce the reliance on fetal bovine serum (FBS) and human platelet lysate (hPL).
Get a Quote