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SHWE-HSB Supplement, Lyophilized
NumberingSHWE-HSB
Product Overviews
SHWE-HSB is a polysaccharide polymer isolated from microalgae. It promotes cell adhesion and proliferation. Unlike traditional extracellular matrices composed of polypeptides (such as RGD) or proteins (like fibronectin and laminin), SHWE-HSB is thermostable up to 100°C and remains stable across a wide pH range (pH 2 to pH 12). NMR analysis confirms that SHWE-HSB is a single, negatively charged polymer with a molecular weight between 280 and 320 kDa.
Application
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Functions as an extracellular matrix to support cell attachment to plastic surfaces.
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Serves as an attachment factor for various adherent cell types.
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Supports the growth of stem cells in 3D cultures, such as hydrogels.
Features and Advantages
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Enhances cell culture performance
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Plant-based and free of animal components
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Provides repeatable and reliable results
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Maintains cellular morphology
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Delivers high quality and high proliferation yields
Figures
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The proliferation of neural stem cell (NSCs) encapsulated in different hydrogels for a period of 14 days. *p <0.05, **p <0.01, and ***p <0.001 between the indicated group (G1: 1mg/ml, G2: 3mg/ml, G3: 5mg/ml) -
Potential clustering behaviors of NSCs encapsulated in four different hydrogels on day 6 and day 14. Red arrows represent the neuro-clusters. -
Left: The average contact angle values for the untreated non-adhesive dish and the HSB-modified dish.
Right: Cell adhesion behaviors of NSCs within 48 hr on the untreated non-adhesive dish and the HSB-modified dish.
References and Citations
Xu, J.; Hsu, S.-h. Enhancement of Cell Behavior by the Polysaccharide Extract of Arthrospira and Potential Biomedical Applications. Molecules 2023, 28, 732. https://doi.org/10.3390/molecules28020732
TDS/COA/MSDS
| Cat. No. | Product | TDS | COA | MSDS |
|---|---|---|---|---|
| SHWE-HSB | Extracellular matrix |
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SHWE-HSB is a polysaccharide polymer isolated from microalgae. It promotes cell adhesion and proliferation. SHWE-HSB has been shown to enhance stem cell growth when incorporated into hydrogels and to promote cell attachment by increasing the hydrophilicity of plastic surfaces when used as a coating.
