SHWE-HSB Supplement, Lyophilized


Product Overviews

Product Overview
SHWE-HSB is isolated from microalgae. The major composition of SHWE-HSB is polysaccharide polymer and is capable of promoting cell adhesion and cellular proliferation. Compared to other extracellular matrices which is composed of polypeptide (RGD) or protein (fibronectin, laminin, etc.), it is thermostable (up to 100°C) and stable between pH 2 and pH12. Based on the NMR analysis, SHWE-HSB is a single polymer with negative charge, and the molecule weight is between 280 to 320KD.

Acts like an extracellular matrix to support cell attachment to plastic dish.
An attachment factor for others adherent cells
Support stem cells to grow in 3D cultures such as hydrogels
Features and Advantages
Improve cell culture performance
Plant-based, animal component-free
Repeatable and reliable results
Maintain cellular morphology
High quality and high proliferation yield


  • The proliferation of neural stem cell (NSCs) encapsulated in different hydrogels for a period of 14 days. *p <0.05, **p <0.01, and ***p <0.001 between the indicated group (G1: 1mg/ml, G2: 3mg/ml, G3: 5mg/ml)
  • Potential clustering behaviors of NSCs encapsulated in four different hydrogels on day 6 and day 14. Red arrows represent the neuro-clusters.
  • Left: The average contact angle values for the untreated non-adhesive dish and the HSB-modified dish.
    Right: Cell adhesion behaviors of NSCs within 48 hr on the untreated non-adhesive dish and the HSB-modified dish.

References and Citations

Xu, J.; Hsu, S.-h. Enhancement of Cell Behavior by the Polysaccharide Extract of Arthrospira and Potential Biomedical Applications. Molecules 202328, 732.


Cat. No. Product TDS COA MSDS
SHWE-HSB Extracellular matrix